Organic sodium salts
![Medchemexpress LLC Benzo[f]quinoxaline-7-sulfonamide, 1,2,3,4-tetrahydro-6-nitro-2,3-dioxo-, sodium salt (1:2) | 479347-86-9 | C12H6N4Na2O6S | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Benzo[f]quinoxaline-7-sulfonamide, 1,2,3,4-tetrahydro-6-nitro-2,3-dioxo-, sodium salt (1:2) | 479347-86-9 | C12H6N4Na2O6S | 25 MG
NBQX disodium is a highly selective and competitive antagonist of the AMPA receptor, exhibiting neuroprotective and anticonvulsant activity. It possesses a high affinity for AMPA and kainate binding sites, with minimal affinity for the glutamate recognition site on the NMDA receptor complex.
- Highly selective and competitive AMPA receptor antagonist
- Exhibits neuroprotective activity
- Shows anticonvulsant activity
- High affinity for AMPA and kainate binding sites
- Little to no affinity for the NMDA receptor complex
Medchemexpress LLC NBQX (FG9202) | 118876-58-7 | C12H8N4O6S | 1 ML
NBQX (FG9202) is a highly selective and competitive AMPA receptor antagonist. It possesses neuroprotective and anticonvulsant activities. NBQX exhibits high affinity for AMPA and kainate binding sites, with minimal or no affinity for the glutamate recognition site on the NMDA receptor complex.
- Highly selective and competitive AMPA receptor antagonist
- Neuroprotective activity
- Anticonvulsant activity
- High affinity for AMPA and kainate binding sites
- Little to no affinity for the glutamate recognition site on the NMDA receptor complex
Medchemexpress LLC CNQX disodium | 479347-85-8 | C9H2N4Na2O4 | 25 MG
CNQX disodium is a potent and competitive antagonist for AMPA/kainate receptors, with IC50s of 0.3 μM and 1.5 μM respectively. It also acts as a competitive non-NMDA receptor antagonist and has been shown to block the expression of fear-potentiated startle in rats.
- Potent and competitive AMPA/kainate receptor antagonist
- IC50 values of 0.3 μM for AMPA and 1.5 μM for kainate receptors
- Competitive non-NMDA receptor antagonist
- Demonstrated activity in in vitro studies, including reversible blockade of Schaffer collateral and mossy fibre excitatory postsynaptic potential (EPSP)
- Demonstrated activity in in vivo studies, showing decreased cocaine responses and partial blockade of stepdown inhibitory avoidance
Pfaltz & Bauer Dimethylglyoxime Sodium Salt 100G | 60908-54-5
Dimethylglyoxime Sodium Salt 100G | 60908-54-5
eMolecules Magnesium ethoxide | 2414-98-4 | MFCD00009060 | 25g
Oakwood Chemical | Magnesium ethoxide | 25g | 537707801 | 099616 | | 2414-98-4 | MFCD00009060 | 114.427 | C4H10MgO2
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Apexbio Technology LLC CNQX 115066-14-3 10mg
CNQX (CAS 115066-14-3) is a selective and competitive antagonist of AMPA and kainate subtype ionotropic glutamate receptors In hippocampal slice preparations superfusion with CNQX at concentrations of 2 5 M reversibly inhibits excitatory post-synaptic potentials mediated by Schaffer collaterals and mossy fibers while preserving both fast and slow GABAergic inhibitory responses In behavioral studies bilateral infusion of CNQX into the amygdala or dorsal hippocampus prior to testing partially suppresses the expression of conditioned avoidance responses with complete blockade observed at specific doses CNQX is widely utilized to dissect excitatory synaptic transmission and investigate non-NMDA receptor functions in neurophysiological and behavioral research
Apexbio Technology LLC NBQX 118876-58-7 10mg
NBQX (CAS 118876-58-7) is a potent and selective antagonist of AMPA-type ionotropic glutamate receptors By inhibiting AMPA-mediated excitatory synaptic transmission NBQX disrupts glutamate-induced neuronal signaling thereby attenuating neuronal injury associated with excessive neurotransmitter release This compound has been widely utilized in preclinical studies to investigate neuroprotective and anticonvulsant mechanisms as well as to model and analyze the pathophysiology of neurodegenerative diseases epilepsy and other central nervous system disorders
Medchemexpress LLC Cnqx | 115066-14-3 | C9H4N4O4 | 50 MG
CNQX is a potent and competitive AMPA/kainate receptor antagonist. It has IC50s of 0.3 μM for AMPA and 1.5 μM for kainate receptors, and also acts as a competitive non-NMDA receptor antagonist.
- Potent and competitive AMPA/kainate receptor antagonist
- IC50s of 0.3 μM for AMPA and 1.5 μM for kainate receptors
- Acts as a competitive non-NMDA receptor antagonist
- Blocks the expression of fear-potentiated startle in rats
- Reversibly blocks Schaffer collateral and mossy fibre excitatory postsynaptic potential (EPSP)
- Selectively reduces the amplitude of the monosynaptic component of DR-VRR
Medchemexpress LLC CNQX disodium | 479347-85-8 | C9H2N4Na2O4 | 5 MG
CNQX disodium (FG9065 disodium) is a potent and competitive AMPA/kainate receptor antagonist. It blocks the expression of fear-potentiated startle in rats and is a competitive non-NMDA receptor antagonist. It is suitable for in vitro and in vivo research.
- Potent and competitive AMPA/kainate receptor antagonist
- Blocks expression of fear-potentiated startle
- Competitive non-NMDA receptor antagonist
- Suitable for neurological disease research
- Inhibitor of ionotropic glutamate receptors
Medchemexpress LLC NBQX disodium | 479347-86-9 | C12H6N4Na2O6S | 50 MG
NBQX disodium (FG9202 disodium) is a highly selective and competitive AMPA receptor antagonist. It exhibits neuroprotective and anticonvulsant activity. This product shows high affinity for AMPA and kainate binding sites, with minimal or no affinity for the glutamate recognition site on the NMDA receptor complex. It has also demonstrated neuroprotective effects in a focal ischaemia model in rats.
- Highly selective and competitive AMPA receptor antagonist
- Possesses neuroprotective activity
- Exhibits anticonvulsant activity
- High affinity for AMPA and kainate binding sites
- Minimal affinity for the glutamate recognition site on the NMDA receptor complex
Apexbio Technology LLC CNQX 115066-14-3 50mg
CNQX (CAS 115066-14-3) is a selective and competitive antagonist of AMPA and kainate subtype ionotropic glutamate receptors In hippocampal slice preparations superfusion with CNQX at concentrations of 2 5 M reversibly inhibits excitatory post-synaptic potentials mediated by Schaffer collaterals and mossy fibers while preserving both fast and slow GABAergic inhibitory responses In behavioral studies bilateral infusion of CNQX into the amygdala or dorsal hippocampus prior to testing partially suppresses the expression of conditioned avoidance responses with complete blockade observed at specific doses CNQX is widely utilized to dissect excitatory synaptic transmission and investigate non-NMDA receptor functions in neurophysiological and behavioral research